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Prospective clinical studies are currently ongoing to assess whether NAC treatment can reduce GSH depletion, correct T-cell-signaling defects and provide clinical benefit to patients with SLE (www.clinicaltrials.gov IND 101320)

Tiredness during the early stages of treatment or after a dose increase is a common and temporary adjustment effect

However, a major challenge with inorganic nanomaterials is their biocompatibility and biodegradability, which can lead to clearance issues and severe toxicity in vivo

As a glutaminase inhibitor, CB-839 is highly sensitive to esophageal squamous cell carcinoma (ESCC), which is highly dependent on glutamine metabolism for energy, providing a new possibility for the treatment of ESCC [69]

10.3389/fneur.2020.00288 111 KumarS.ReddyP