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Phase 3 clinical trials demonstrated a significant reduction in visceral fat without major metabolic side effects (Falutz et al., J Clin Endocrinol Metab 2010)

To test the requirement of CYP18A1 in our system, we depleted CYP18A1 using the GAL4/UAS system and assessed the response to APAP treatment

Targets 95 ToyotaM.SuzukiH.SasakiY.MaruyamaR.ImaiK.ShinomuraY.et al (2008)

5-Htr3 and 5-Htr4 located on the mitochondrial membrane and functionally regulated mitochondrial functions

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