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SGLT-2 inhibitors have a well-established association with genital mycotic infections, while the evidence for increased UTI risk is mixed

Results from the phase 2 TROPION-Lung05 trial published in the Journal of Clinical Oncology revealed that among 137 patients given 6 mg/kg of dato-DXd every 21 days for pretreated NSCLC, the confirmed ORR was 35.8% (95% CI, 27.8%-44.4%), including 32.8% of patients experiencing a partial response and 2.9% having a complete response

doi:10.1016/S2215-0366(24)00360-2

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Reconstitute the freeze-dried powder Freeze-dried powder refers to the process of converting drugs into powder through freeze-drying technology in order to better preserve their activity