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Additionally, obesity and overweight are widespread: a recent report estimates that roughly 39% of adults are now obese worldwide (30% globally overweight or obese) ( [26] ), and projections suggest over half of the worlds population (4 billion people) could be obese by 2035 ( [26] )

Many breast cancer treatments, particularly certain chemotherapy regimens and hormonal therapies like tamoxifen or aromatase inhibitors, can contribute to weight gain and metabolic syndrome, making diabetes management more complex

Targeted MRM-based methods are most easily developed with the availability of purified proteins, whereas untargeted DDA analyses offer a more flexible, universal application without time-consuming optimization steps

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