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Learn about GHK-Cu Topical Serum Collagen remodeling: GHK-Cu upregulates COL1A1 and COL3A1 gene transcription

O., Mayfield, J

Toxicol Appl Pharmacol 285(2):136148 McKinsey TA, Foo R, Anene-Nzelu CG, Travers JG, Vagnozzi RJ, Weber N, Thum T (2022) Emerging epigenetic therapies of cardiac fibrosis and remodelling in heart failure: from basic mechanisms to early clinical development

Weight of evidence: Overall evidence is ModerateHigh in FR- Ab + children

Studies have shown that when amyloid-beta and tau are increased, the cells ability to neutralize oxidative stress and mitochondria specific ROS is decreased leading to further tau hyperphosphorylation and neurodegeneration (Alavi Naini and Soussi-Yanicostas 2015)