There are many other potential selective NOX inhibitors (e.g., fulvene-5, triphenylmethane derivatives, celastrol, some synthetic diarylheptanoids, grindelic acid, dietary flavonoids, shionogi I and II, and perhexiline)
(2012) in Journal of Aging Research confirmed that GHK-Cu increased skin density and thickness, counteracting the natural decline in GHK-Cu levels (from 200 ng/ml at age 20 to 80 ng/ml at age 60) that exacerbates wrinkles (Pickart et al., 2012)
The peptide stimulates production of collagen types I, III, and IV , the primary structural proteins responsible for skin firmness and resilience
Aging Cell (2023)
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