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Some researchers keep a 5mg vial specifically for the first two weeks at 1mg (using just 20 units per dose), then switch to larger vials for the remainder of the protocol

I take supplements to get me in the above normal range for everything and vitamin D I was told to aim for 100 by a B12 consultant

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That long half-life is also why titration steps are held for about four weeks rather than a few days: it takes several weekly doses for blood levels to plateau at each new rung of the ladder before the next increase makes sense

Characterising the Expression and Function of CCL28 and its Corresponding Receptor, CCR10, in RA Pathogenesis