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The activation of the Nrf2 pathway triggers a massive endogenous production of Phase II detoxification enzymes, including Heme Oxygenase-1 (HO-1) and NAD(P)H quinone oxidoreductase 1 (NQO1)

2024;108(7):e1218

It has been shown that antagonistic crosstalk between SIRT1 and NF-B is present to regulate energy metabolism and innate immunity (Liao et al

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