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Documented Long-Term Side Effects of Corticosteroids Bone loss and fractures due to calcium and vitamin D depletion and impaired osteoblast activity (2) Blood sugar dysregulation and steroid-induced diabetes through increased insulin resistance and gluconeogenesis (3) Muscle wasting and impaired connective tissue repair from protein catabolism and suppressed synthesis (4) Weakened immunity, delayed healing, and prolonged infections related to micronutrient depletion and immune suppression (5) Weight gain, mood changes, and insomnia driven by hormonal and circadian disruption (6,7) Abnormal blood lipids, hypertension, and increased cardiovascular risk , including heart attack, with long-term use (8) Thinning skin and easy bruising from collagen breakdown and connective tissue loss (9) Psychiatric effects , including anxiety, irritability, depression, andin severe casessteroid-induced psychosis, particularly at higher doses or with prolonged exposure (10) Even short-term corticosteroid use can cause side effects in susceptible patients
However, because of individual differences in absorption and metabolism, the dose required to achieve complete, around-the-clock control varies from patient to patient
Recent research has thoroughly examined the connection between abnormalities in lipid metabolism and the development of atherosclerosis in people with T2DM
B12 shots may support weight loss by boosting energy levels and metabolism, especially in individuals with a B12 deficiency
Vitamin B12 is water-soluble, which means the body takes what it needs, and the rest passes harmlessly through the body
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