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Ohanyan et al

GLP-1 effects in certain areas of the brain ultimately lead to weight loss, and in addition to the cardioprotective and renoprotective effects discussed in this article, evidence also points towards neuroprotective and other medically desirable properties (Mller et al., 2019

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Key Differences at a Glance Dosing Wegovy pill: Daily tablet on an empty stomach Injectable GLP-1s: Weekly self-injection Weight Loss Wegovy pill: ~1317% at 64 weeks Injectable GLP-1s: ~15%+ at 68 weeks Blood Sugar Impact Wegovy pill: Strong effect on insulin resistance with modest A1c reduction Injectables: Slightly greater A1c reductions overall Side Effects Wegovy pill: Similar GI effects (nausea, diarrhea)