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Individual response depends on genetics, starting dose, rate of dose escalation, and overall health

When initiating Ozempic or Rybelsus tablets, consider reducing the dose of concomitantly administered insulin secretagogue (such as sulfonylureas) or insulin to reduce the risk of hypoglycemia Semaglutide delays gastric emptying and has the potential to impact the absorption of other oral medications

Diabetes & metabolism, 39(5), 445453

Maintenance dose in patients with type 2 diabetes mellitus and chronic kidney disease: After at least 4 weeks on the 0.5 mg dose, increase to 1 mg subcutaneously once a week

That said, sometimes switching medications has benefits, even when both drugs are the same ingredient sold under a different brand name