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Preclinical Research: Animal studies have demonstrated that GLP-1 agonists can reduce drug-seeking behavior in rodent models of cocaine and opioid addiction

For context, the Phase 2 NEJM result at 24 weeks was 17.5% at the same 12 mg dose

Many patients in Florida use compounded GLP-1 medications , which are prepared in licensed pharmacies and provided in vial form for flexible dosing

The clinical criteria for determining eligibility for the Medicare GLP-1 Bridge are somewhat more restrictive than the FDA approvals, however, and include Part D enrollees with a BMI of 35 or more

Adding a ketogenic diet on top of an SGLT-2 inhibitor on top of a GLP-1 agonist creates a triple threat for excessive ketone production that can tip into dangerous territory