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The project co-led by Timothy Marlowe, PhD, associate professor in the Department of Internal Medicine , the U of A Cancer Center and the College of Pharmacy, Michael Fallon, MD, FACP , executive director for Clinical Research and chair of the Department of Internal Medicine, and Hyo Jin Park, PhD, assistant research scientist in the Department of Internal Medicine targets the connection between focal adhesion kinase (FAK) and paxillin, two proteins that become hyperactive during fibrosis and fuel the buildup of scar tissue in the liver

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Risks include injection site reactions, rare allergic responses, and hypokalaemia during treatment of severe anaemia

For skin, the primary mechanisms include stimulation of collagen I and III synthesis, increased production of decorin (which organizes collagen fibers), upregulation of VEGF for blood vessel formation, and activation of tissue remodeling through metalloproteinase regulation

ISBN 978-0-7817-6507-7