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Malignant peripheral nerve sheath tumors were stratified into low and high grades based on the previously published criteria 18 with high grade corresponding to tumors with hypercellularity, cytologic anaplasia, and a maximal mitotic index greater than 6/10 high-power fields, often accompanied by necrosis

For 28 days, animals were divided into four groups and treated daily with either LC (300 mg/kg), TMX (100 mg/kg), or both at the aforementioned doses

DNA methylation of PGC-1 is associated with elevated mtDNA copy number and altered urinary metabolites in autism spectrum disorder

Weight loss : Improves fat metabolism, supports glucose regulation, and may inhibit myostatin, a protein that limits muscle growth

Its ability to enhance synaptogenesis, accelerate wound healing, and protect neurons positions it as a frontier therapy in age-related decline