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Unlike traditional sexual-enhancement drugs, PT-141 works directly at the level of the brain, eliciting a natural sexual response by interacting with the hypothalamus

(2019) 51:e13396

Histological analysis showed that FOXO4-DRI treatment improved the testicular microenvironment, leading to thicker seminiferous epithelia, increased spermatogenic cells, and more mature spermatozoa in the central lumen