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Injections or pre-filled pens should be administered weekly subcutaneously (under the skin, in areas such as the thighs or upper arms)

Studies were also excluded if they focused on participants with primary testicular disease, including Klinefelter syndrome, testicular tumors, or severe varicocele, or if they involved men with pituitary or hypothalamic organic diseases, such as prolactinomas or hypopituitarism

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Clinical trials have demonstrated significant weight loss with semaglutide, with studies reporting an average body weight reduction of approximately 13.7% [1]