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Sodiumglucose co-transporter 2 (SGLT2) inhibitors exert hypoglycaemic effects by inhibiting glucose reabsorption at the proximal convoluted tubules, causing glycosuria, natriuresis and volume contraction (Figure 1).5 Besides SGLT2 inhibition, incretin-based therapies have also been used in recent years for the treatment of T2D ( Figure 2 )

There are several salutary effects this hormone has in the body

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The drugs success played a pivotal role in Novartis raising its 2024 earnings guidance for the third time

A weight reduction of 15% or more at 13 weeks was achieved by 31.2% of those receiving 10 mg VK2735 and 41.5% of adults receiving the 15 mg dose