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The concept of neurogenic inflammation within the dura mater serving as a catalyst and perpetuator of acute migraine episodes has been considered for many years

High blood pressure (hypertension) is usually regulated by angiotensin-converting enzyme (ACE) via the kinin-kallikrein system (KKS) and the renin-angiotensin-aldosterone system (RAAS)

however, an overarching goal of the gene therapy is to restore vision to some degree in patients with glaucoma and a rarer eye condition called non-arteritic anterior ischemic optic neuropathy (NAION)

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The production of free radicals also increases during illness, which can result in complications