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Pull on the plunger to withdraw the correct dosage of vitamin B12 into the syringe chamber

To identify mediators of disordered metabolism in PBH, we analyzed the plasma metabolome in the fasting state and 30 and 120 minutes after mixed meal in 3 groups: PBH ( n = 13), asymptomatic postRoux-en-Y gastric bypass (post-RYGB) ( n = 10), and nonsurgical controls ( n = 8)

Saxenda, Wegovy, and Zepbound patients are included regardless of obesity diagnostic claims

accepted April 7, 2025

We look at what the dose-dependent timing says about when risk peaks during titration (Section 5.1), the mechanism that makes the link biologically plausible (Section 5.2), what the treatment response tells us about management (Section 5.3), where the case fits against existing pharmacovigilance data (Section 5.4), and what it means at the bedside (Section 5.5)