glp 1 for chronic fatigue GLP-1 Drugs & What They Do 059 - Ozempic and Wegovy

10.1074/jbc.M301403200 294

When Side Effects Affect Weight Loss Results Some patients assume more nausea means better weight loss

These are worst during the first 1-2 weeks at each new dose and usually improve

The results showed no clinically relevant differences in total exposure (AUC) between the abdomen, thigh, and upper arm

Side Effects Profile All three medications share common side effects, primarily gastrointestinal: Nausea (usually temporary, worst in first few weeks) Diarrhea or constipation Abdominal discomfort Reduced appetite (this is the goal, but can feel uncomfortable initially) The higher dose of Wegovy may cause more pronounced side effects initially, while Saxendas daily dosing can offer more stable blood levels with potentially fewer ups and downs