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To prevent the contribution of dilution effects, metabolite data were mean-centered and the intensities of the spectral peaks of each given sample were normalized to the sum of all metabolite concentrations

For instance, insulin is essential for helping many people with diabetes control their blood sugar, while GLP-1s have helped millions of people reach a healthier weight

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On the contrary, microsomal GSTs, also known as MAPEG (membrane-associated proteins involved in eicosanoid and glutathione metabolism), are integral membrane proteins which are not evolutionary related to the other major classes