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Pantoprazole can be an effective tool for managing the digestive side effects that are often the biggest hurdle in the early stages of GLP-1 therapy

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The analysis also revealed sex-specific differences

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It also improves endothelial function by lowering ET-1 and thromboxane B2 levels while increasing CGRP levels, inhibits apoptosis by modulating B-Cell Lymphoma-2 (Bcl-2), Bcl-2-associated X protein (Bax), and caspase-3 expression, and suppresses NOD-like receptor protein 3 (NLRP3) inflammasome activation via the toll-like receptor 4 (TLR4)/NF-B signaling pathway (Guo et al., 2015)