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Following the availability of data from these various studies, and data on c-MET expression as a biomarker that indicates a poor prognosis in patients with gastrointestinal cancer and increased c-MET expression, inhibitors targeting this pathway have entered the clinic in the past decade

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According to Dods and Butler, the emergence of overtourism is driven by the tipping point of public resistance to tourism and the transformation of almost every area into a tourist destination