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Despite their clinical efficacy, most GLP-1-derived peptides require parenteral administration (with oral semaglutide being the exception) and frequently induce gastrointestinal adverse events that limit long-term adherence (Aroda et al., 2019

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This perspective extends glutathione biology beyond classical oxidative stress, highlighting its essential role in protecting cardiac tissue and preserving resilience under metabolic and ischemic challenges

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This not only affects individual health and quality of life but also has implications for the communitys healthcare system