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Differential expression of CYP2j2 gene and protein in Camelus dromedarius
As tau becomes hyperphosphorylated, its capacity to support microtubule assembly and stability diminishes, resulting in increased levels of unbound tau that may aggregate into tangles (if not secreted or degraded in the lysosome) [107]
The observed improvement in tear film stability, as measured by TFBUT, is particularly relevant given G-OSD is predominantly associated with Meibomian gland dysfunction (MGD), leading to an evaporative form of DED characterized by poor tear film stability ( In our cohort, glutathione use was associated with reduced ocular surface damage, as indicated by NEI-SS scores