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All potential participants provided written, informed consent prior to participation as per approval provided by the Western University Health Sciences Research Ethics Board, London, Ontario

Differential expression analysis was performed using limma-voom, and significance was determined using two-sided statistical testing with multiple-comparison correction (adjusted P value)

Beyond inducing weight loss, these treatments have demonstrated benefits on obesity-related complications, including neuropsychiatric and substance use disorders, peripheral vascular disease, arthritis, MASLD, hypertension and renal disorders, positioning them as a central focus in current obesity research [3]

Increases energy levels and detoxifies the liver Vitamin C combats harmful substances and toxins

For those with a B12 deficiency and an MTHFR mutation, one major advantage of B12 injections is that they are readily absorbed in the body and do not have to be taken as often as oral tablets