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Regulating HO-1 activity could be an effective strategy in treating diabetic foot ulcers, given its significance in every stage of wound healing

doi: 10.1016/S0002-9343(01)00980-9 101 de Lima BeltroFEde Almeida BeltroDCCarvalhalGde Lima BeltroFEde Souza Braga FilhoJde Brito OliveiraJet al

One possible interpretation of the available agonist-bound non-conducting KAR structures in pseudo four-fold and asymmetric LBD conformation is that they represent different steps of the desensitization process, which starts similar to AMPARs, with the rupture of D1-D1 interfaces in two intact LBD dimers, followed by dissociation of one LBD dimer and then the second (Zhou et al., 2025)

Mental health effects deserve mention

Am J Physiol Endocrinol Metab (2012) 302(12):E145360