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On the calorie side, research has shown positive benefits from an energy surplus ranging from around 100 extra calories per day up to 1,000.32 The key is to evaluate your metabolism as closely as possible and adjust your caloric intake to slightly exceed the burn you get from your weight training

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This effect likely relates to delayed gastric emptying, as high-fat foods naturally slow digestion further, potentially causing discomfort or early satiety

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Preclinical and clinical trials should be designed accordingly, with a focus on conditions where antioxidant therapy is more likely to yield therapeutic benefit