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Last reviewed: May 15, 2026 Last updated: May 15, 2026 Written by: Jay Hastings , CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

Live bacteria actively colonize the gut and create the disruption necessary for microbiome change

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This is worth knowing as a clinician because a patient adjusting to a new or increased dose of a GLP-1 may experience reduced appetite and energy, which could affect their participation in therapy

That is why its important to only take under the supervision of a doctor