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Brubaker says drugs need to be carefully tested in stages before they are approved for use in people

Spares glycogen: By using fat as fuel, the body conserves limited glycogen stores during exercise

If you develop diarrhoea after starting B12 supplementation, it is worth considering other factors that may be contributing to your symptoms

Neither should be ignored

Ethics declarations Ethics approval and consent to participate Manuscripts reporting studies involving human participants, human data, or human tissue must: The procedures and data collections in human study have been approved by Institutional Review Board of National Taiwan University Hospital (201507055MINC, 201712030RIND), and all participants signed a written informed consent form