found that lycopene pre-administration could modulate the TLR4/TRIF/NF-B pathway by significantly downregulating the expressions of TLR-4, TRIF, phosphorylated p65 proteins, which in turn suppresses the production of inflammatory cytokines IFN-, TNF-, IL-6, and IL-1 in colonic tissue, thereby reducing inflammation response in the context of UC(48)
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Our previous study also showed that BHBA was able to promote BDNF expression under normal energy supply ( Bdnf transcription in active or repressive ways, leading to changes of promoter occupancy and BDNF expression ( Bdnf gene contains nine exons, each of which is regulated by its promoter
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Efficient bioproduction of 5-aminolevulinic acid, a promising biostimulant and nutrient, from renewable bioresources by engineered Corynebacterium glutamicum