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For patients who have had a cardiovascular event and heart failure, SGLT2 inhibitors are recommended as first-line treatment, GLP-1 RAs or metformin as second-line treatment, and DPP4 inhibitors, acarbose, or insulin as third-line treatment [5]

Ketones form as a result, which serve as an alternative source of energy for the brain, heart and muscle

doi: 10.4236/ABB.2013.42A037 40 DimriR.MallS.SinhaS.JoshiN

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