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In good agreement, the association between an OCTN2 SNP (rs27437), down-regulating the OCTN2 expression and the CRC risk has been identified (Zou et al., 2018)

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Results We found that ALCAR reduces cell proliferation, induces apoptosis, hinders the production of pro inflammatory cytokines (TNF- and IFN-) and of chemokines CCL2, CXCL12 and receptor CXCR4 involved in the chemotactic axis and impairs the adhesion, migration and invasion capabilities of PCa and BPH cells in vitro

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