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Recently, Bourke and colleagues assessed developmental changes in normal brain regional volumes relative to head size and reported that by adolescence, grey matter volume decreased while white matter volume increased

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Furthermore, TMAO promotes diabetes by elevating fasting insulin, increasing insulin resistance (HOMA-IR), and inducing adipose tissue inflammation, contributing to glucose metabolism dysfunction and heightened cardiovascular event risks in diabetic patients (Subramaniam and Fletcher, 2018)