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GIP receptor activation complements the effects of GLP-1, further enhancing satiety and helping the body process and store nutrients more efficiently

The increase in risk was small approximately three to four additional cases per 10,000 patients treated with GLP-1s over 18 months, but clinicians and patients should be aware of this potential association. Researchers said while the risk is low, the rising use of GLP-1s in patients with and without Type 2 diabetes warrants special attention to medication safety

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The greatest effects on gastric motility appear to occur during treatment initiation, dose escalation phases, and higher-dose maintenance therapy