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Negative Effects A study from the University of Colorado Anschutz Medical Campus found that GLP-1 RAs are associated with an increased fracture risk in obese patients without diabetes, particularly in those with a body mass index (BMI) over 40 and aged over 68

Given the well-established role of the GLP-1 pathway in T2D management, CT-388 could potentially fit within the current standard of care in several ways: Weight Loss : CT-388 has demonstrated significant, rapid, and dose-proportional weight loss in the trial subjects, which is a key therapeutic goal in both obesity and T2D management

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However, understanding what the evidence does and does not show and knowing when to seek help is essential for anyone participating in a retatrutide clinical trial