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Fatih Terzi (Istanbul Technical University) 327 Urban Digital Twins for Cities in Transition: A Literature Review on Current Applications and Future Perspectives Cities in transition are urban environments undergoing profound transformations to address some of the most pressing global challenges, including climate change, socio-economic inequality, rapid urbanization, and the urgent need for sustainable development

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The free apo-peptide binds copper(II) with high affinity through its N-terminal amine, the histidine imidazole nitrogen, and the deprotonated amide nitrogen, forming the GHK-Cu species that figures in much of the published literature

doi: 10.1016/j.jss.2010.03.038 35