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The GLP-1 hormone is produced by specialized intestinal cells, primarily in the small intestine and colon, shortly after food enters the digestive tract

More than half of Americans taking GLP-1s say it was difficult to afford

In a clinical study involving patients with type 2 diabetes, an almond-based diet with a low-carbohydrate content, which had been previously shown to possess marked prebiotic properties [110, 111], resulted in augmentation of the number of SCFA-producing bacteria species, such as Roseburia , Ruminococcus and Eubacterium , which led to an increase in fasting blood GLP-1 levels and also promoted antidepressive effects after three months [112]

But the critical distinction is what lean mass actually means

Roles of hormones in taste signaling