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Statins deplete GPX4 expression and mevalonate rescues statin-induced cell death The remarkable overlap between the transcriptional changes induced by RSL3 and simvastatin in both YR1.7 and MC38 led us to question whether statins might also act on GPX4 to promote ferroptosis

Although theres a small amount of evidence to support the use of chanca piedra for kidney stones in humans, larger and more rigorous human studies are needed to determine if chanca piedra truly has any benefits

Aktas et al., 2012

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MPs are recognized by the immune system either as particulate foreign bodies or via their low-molecular-weight soluble components (e.g., plasticizers, bisphenols), which mimic damage-associated molecular patterns (DAMPs)