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[180] The tapering schedule may depend on the duration of therapy, with slower tapering required for patients who have received treatment for extended periods

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Thus, the residues forming the dimeric interface should also constitute a good criterion for distinguishing monomeric from dimeric proteins

In addition to PARK6 (encoding PINK1) and PARK2 (encoding Parkin), other genes associated with Parkinsons disease, such as PARK7 (encoding the DJ-1 protein) and PARK8 (encoding the LRRK2 protein), are also thought to be mutated in patients with Parkinsons disease (Walter et al., 2019)