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In the largest and longest follow-up study to date (up to 12 months), patients with mild AD underwent FUS targeting the hippocampus, frontal, and parietal lobes, with no serious adverse events, full BBB closure within 48 h, and cognitive outcomes comparable to those seen with natural disease progression (Rezai et al., 2022)

Recent statistics report a global prevalence of 32.40% and an annual incidence rate of 4.69%

The freezing tolerance assay was performed using 14-day-old seedlings, which were pre-treated at 4C for 3 days, exposed to 10C for 5 h, thawed at 4C for 12 h, and then recovered at 22C for 5 days before counting survival rate

Its good practice to let the vial sit at room temperature for a few minutes before adding the BAC water

Refrigeration is advisable for long-term storage (612 months or more), especially in hot climates