First, the heterogeneity between the model and the population is a key factor: preclinical studies are often conducted in animal models of a single disease (such as Diabetes Mellitus or senility), and the intervention dosage and duration are often optimized to highlight the muscle-preserving effect [60]
Serious side effects are rare but include acute pancreatitis (severe abdominal pain) and gallbladder issues
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Evaluation of a multi-parameter biomarker set for oxidative damage in man: increased urinary excretion of lipid, protein and DNA oxidation products after one hour of exercise
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