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This is why it is important to select an area with a sufficient pinch of fat, such as the abdomen (at least two inches away from the belly button), the front of the thighs, or the back of the upper arm

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10.1186/s12882-025-04103-5 51 MaD.WangD.YuJ.HuangN.LuoN.YangY.et al (2025b)

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Additionally, dehydration resulting from gastrointestinal side effects may contribute to muscle cramping and joint stiffness