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The development program runs from Phase 1b through three completed Phase 3 readouts, with several more ongoing

Among HDAC isoforms, HDAC3 appears particularly important in mediating butyrates anti-inflammatory effects in macrophages (Jiang et al., 2025)

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Peppermint tea can also soothe digestive discomfort, though patients with gastroesophageal reflux should use it cautiously as it may relax the lower esophageal sphincter