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CagriSema, developed by Novo Nordisk, is a fixed-dose combination of cagrilintide (a long-acting amylin analog) and semaglutide (a GLP-1 receptor agonist)
10.1016/j.neubiorev.2016.02.011 10
doi: 10.1016/j.jtemb.2018.03.007 25 GaoGLiJZhangYChangYZ
60 In contrast, the long-acting enzyme resistant form of GLP-2, namely (Gly2)GLP-2, did not provide benefit on bone strength in a mouse model of bone fragility, 61 despite promoting the expression of bone matrix genes and reducing osteoclast number in the in vitro setting
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