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Glutathione helps protect those mitochondria so cells can keep producing energy and repairing themselves

bioRxiv Preprint, (2021)

[DOI] [PubMed] [Google Scholar] 52.Moreira P.I., Harris P.L., Zhu X., Santos M.S., Oliveira C.R., Smith M.A., Perry G

In our experiments, the concentration of CB-839 needed for effective, functional glutaminase inhibition varied from 10 nM to 1 M, and the antiproliferative IC 50 was determined as 0.41 M for the HG-3 cell line and 66.2 M for the MEC-1 cell line