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Notably, cysteine is also essential in animals with mutations in either cystathionine -lyase (CSE, also known as CTH and CGL) or cystathionine -synthase (CBS), enzymes of the trans -sulfuration pathway 12,13 (Fig

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The appropriate response to that uncertainty is not to abandon the compound but to use it within a structured clinical framework: defined goals, evidence-appropriate dosing, quality-assured sources, systematic monitoring, and ongoing reassessment as the science matures

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