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Dapagliflozin, when used as a component of XIGDUO XR, is indicated in adults with type 2 diabetes mellitus to reduce the risk of: Sustained eGFR decline, end-stage kidney disease, cardiovascular death, and hospitalization for heart failure in patients with chronic kidney disease at risk of progression

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Expected weight loss with the -enatides is only around 34 pounds, which is far less than with -glutides

Persistently absent periods need evaluation for pregnancy, premature ovarian insufficiency, or other causes