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Targets GLP-1 and GIP receptors, showing even greater weight loss than Ozempic in some studies

Psychological factors: Anxiety about injury, frustration with limitations, depression from activity restrictions all common and impactful

This makes the tablet form Wegovy the first oral GLP-1 approved for weight loss on the market, spurring a new wave of marketing from the manufacturers

You can even take a look at essential baseline laboratory tests that are often needed prior to your first dose

In a 2026 clinical trial published in Nature Medicine , participants who switched from injectable GLP-1 drugs to the once-daily pill orforglipron maintained roughly 75% to 79% of their prior weight loss