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Statements Acknowledgments This work was supported by grants from Federico II University of Naples (Italy)

The trial enrolled 76 adults with type 2 diabetes and randomized them to placebo, a three-strain formula or the five-strain formula now sold as Glucose Control After 12 weeks, the group taking the five-strain probiotic saw a statistically significant improvement in post-meal blood sugar spikes and total glucose response after a test meal compared with the placebo group

Meijering E, Jacob M, Sarria JC, Steiner P, Hirlmg H and Unser M (2004) Design and validation of a tool for neurite tracing and analysis in fluorescence microscopy images

The TTD database provides information about the known and explored therapeutic protein and nucleic acid targets, the targeted disease, pathway information, and the corresponding drugs directed at each target (Wang et al., 2020)

Population characteristics For this study we utilized data from two independent study cohorts that were consented and sampled 10 years apart